SKIP TO CONTENT
Breanne J. Kincaid, Ph.D.
Assistant Toxicologist/Regulatory Scientist
T: 202-557-3833
F: 202-557-3836
Overview
Breanne J. Kincaid, Ph.D., is Assistant Toxicologist and Regulatory Scientist with The Acta Group (Acta®). Dr. Kincaid is an environmental toxicologist whose work integrates human health hazard assessment, computational toxicology, and regulatory science. Her expertise includes the application of in vitro microphysiological systems, in silico modeling, and systematic evidence evaluation to characterize chemical hazards and support scientifically robust risk assessment. Dr. Kincaid's combination of toxicological training, computational expertise, regulatory awareness, and strong technical communication skills enables her to support clients in preparing, analyzing, and interpreting environmental, toxicity, and public health data to facilitate product approvals, regulatory compliance, and informed business decision-making.
Dr. Kincaid has substantial experience conducting multidisciplinary toxicological research and managing complex scientific projects. Her research has focused on the development and application of new approach methods (NAM), including human organoid models, quantitative structure-activity relationship (QSAR) approaches, cheminformatics, exposure and biotransformation modeling, and computational hazard assessment tools. She has designed and executed studies evaluating the developmental neurotoxicity potential of chemical mixtures and commercially significant compounds, while developing expertise in data analysis, systematic review methodologies, and integration of diverse toxicological evidence streams. Dr. Kincaid supports clients in developing regulatory data for submissions under the Toxic Substances Control Act (TSCA), Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), and related chemical management programs, and provides deep technical knowledge to support clients in advocating for the application of the best available science throughout the regulatory decision-making process.
Professional and Community Involvement
- Member, Society of Toxicology (SOT), 2020 – present
- Member, International Microphysiological Systems (MPS) Society, 2022 – 2026
- American Society for Cellular and Computational Toxicology (ASCCT), 2023 – 2026
Articles and Writings
Kincaid B., Zhang J., Ebert A., Alam-El Din D., Martinez Lopez C., Liard J., Schenke M., Romero C., Kleensang A., Maertens A., Hartung T., & Smirnova S. Low dose exposure to defined mixture of inorganic contaminants shows no evidence of synergistic neurotoxicity in a human brain organoid model. (In Review)
Kincaid B., Sumner J., Zhang J., & Smirnova L. Pynapse: a computational tool for four-marker quantitative synapse detection in densely labeled 3D neuronal images. (In Review)
Wang Y., Egert A., Schenke M., Smirnova L., & Kincaid B. (2026). Developmental Neurotoxicology From Regulatory Testing Perspective: History, Achievements and Challenges. In C. A. McQueen (Ed.), Comprehensive Toxicology (4th edition), 287-312. Elseiver. DOI:10.1016/B978-0-323-95488-4.00187-X
Rittenhouse A., Krall C., Plotkin J. D., Alam El Din D. M., Kincaid B., Liard, J., & Smirnova L. (2025). Microglia-containing neural organoids as brain microphysiological systems for long-term culture. Frontiers in Cellular Neuroscience, 19, Article 1616470. DOI: 10.3389/fncel.2025.1616470
Education
- BS, Biology, BA, Government, Georgetown University, 2016
- Sc.M., Environmental Health, Johns Hopkins Bloomberg School of Public Health, 2021
- Ph.D., Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, 2026
Rankings & Recognition
- Johns Hopkins CERSI Scholar, 2025