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March 8, 2022

UK HSE Opens Call For Evidence For Four Substances


The Health and Safety Executive (HSE), in conjunction with the Environment Agency, has assessed 11 substances and substance groups that were added to the EU REACH Candidate List. As a result, the agencies have identified the following four substances, or substance groups, that require regulatory management options analysis (RMOA):

Substance Name

Identified Uses

Dioctyltin dilaurate, stannane, dioctyl-, bis(coco acyloxy) derivs., and any other stannane, dioctyl-, bis(fatty acyloxy) derivs. wherein C12 is the predominant carbon number of the fatty acyloxy moiety (DOTL)

[substance group, typically manufactured using dioctyltin oxide and coconut fatty acids or commercial “lauric acid” as starting materials in the ratio 1:2]

Catalyst in the manufacture of a variety of polyurethane applications, including rigid foams, varnish and powder coatings, and sealants. DOTL-based products also catalyze processes for manufacturing polyester polyols and other polyester products such as the cross-linked low-density polyethylene cable insulation that is used for communications applications and high-voltage power cables that may be used underground, overhead, across the oceans, or in buildings, tunnels, vehicles, ships, and trains.


Solvent in the production of lacquers, varnishes, cleaning and detergent preparations, adhesives, cosmetics, deodorant fumigants, emulsions and polishing compositions, pulping of wood, extraction medium for animal and vegetable oils, laboratory chemical (eluent in chromatography), cassettes, plastic and rubber, and insecticides. May form as a contaminant in consumer products such as plastics, detergents, and cosmetics.

Small brominated alkylated alcohols (SBAA)

[substance group:

  • 2,2-Bis(bromomethyl)propane1,3-diol (BMP) (CAS RN 3296-90-0)
  • 2,2-Dimethylpropan-1-ol, tribromo derivative/3-bromo-2,2- bis(bromomethyl)-1-propanol (TBNPA) (CAS RNs 36483-57-5 and 1522-92-5). CAS 36483-57-5 contains three substructures, where one of them is CAS 1522-92-5.
  • 2,3-Dibromo-1-propanol (2,3-DBPA) (CAS RN 96-13-9)]

BMP — Reactive flame retardant in polymer resins.

TBNPA — Reactive intermediate for high molecular weight flame retardants, reactive flame retardant for polyurethanes, and may also be present in polymer preparations supplied to consumers.

2,3-DBPA — Intermediate in the preparation of flame retardants, insecticides, and pharmaceuticals.

Phenol, alkylation products (mainly in para position) with C12-rich branched or linear alkyl chains from oligomerization, covering any individual isomers and/or combinations thereof (PDPP)

[substance group, including but not limited to:

  • Phenol, 4-isododecyl- (CAS RN 27459-10-5)
  • Phenol, tetrapropylene- (CAS RN 57427-55-1)
  • Phenol, 4-dodecyl-, branched (CAS RN 210555-94-5)
  • Phenol, (tetrapropenyl) derivatives (CAS RN 74499-35-7)
  • Phenol, 4-isododecyl- (CAS RN 27147-75-7)
  • Tetrapropenyl phenol
  • 4-(3,4,5,6-Tetramethyloctan-2-yl)phenol
  • 4-(3,4,5-Trimethylheptyl)phenol
  • Phenol, alkyl branched (species comprising decyl, undecyl, dodecyl, tridecyl, tetradecyl, pentadecyl substituents)
  • Phenol, para-alkylation products with C12-rich branched olefins from propene oligomerization]

Chemical intermediate in the production of lubricant additives, hydraulic oils, and fuel system cleaners; synthetic rubbers, tires, and floor coatings; paints, printing inks, varnishes, epoxy, and phenolic resins.